WHAT IS LUPUS?

What is Lupus?

What is Lupus?

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Lupus is an autoimmune disorder where the body's natural defense system erroneously targets its own tissues, leading to inflammation, swelling, and destruction. This disorder can influence various bodily systems, including the skin, joints, kidneys, heart, and brain.


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There are various forms of lupus, with Systemic Lupus Erythematosus (SLE) being the most prevalent form. Other variations of lupus include discoid lupus, which mostly impacts the skin, and drug-induced lupus, caused by certain medications.

The Origins of Lupus

The precise cause of lupus remains unclear, but experts believe it results from a combination of genetic, environmental, and hormonal factors. Individuals with a family history of lupus could be at increased risk of developing the disease.

Environmental triggers including sun exposure, infections, or certain medications can activate lupus in individuals who are already vulnerable. Hormones also contribute, which is why lupus is seen more often in females, especially between the ages of 15 and 44.

Lupus Symptoms

Lupus appears with a wide range of signs, which may differ from individual to individual. The most frequent symptoms consist of:

Fatigue: Overwhelming fatigue is a highly reported symptoms in those with lupus.
Joint pain and swelling: Many individuals report pain, stiffness, and swelling in their joints, usually when they wake up.
Skin rashes: A characteristic rash across the cheeks and nose is a typical sign of lupus, but rashes can show up in other parts of the skin.
Fever: Random fevers may occur without any obvious cause.
Hair loss: Hair loss is prevalent in lupus patients, and some may even suffer from patchy hair loss.

In severe cases, lupus can lead to complications in vital organs, impacting the kidneys, heart, and lungs.

How Lupus is Diagnosed

Identifying lupus can be difficult because its symptoms mimic those of a variety of disorders. Physicians use a combination of lab work, imaging studies, and medical assessments to make an accurate diagnosis.

Some tests used consist of:

Antinuclear antibody (ANA) test: An abnormal ANA level may suggest an autoimmune disorder, although it’s not specific to lupus.
Erythrocyte sedimentation rate (ESR): This screening detects inflammation in the body and is often elevated in people with lupus.
Urinalysis: Looking for irregularities in urine can help detect kidney involvement in lupus.

Managing Lupus

Since lupus is incurable, therapies are available to reduce symptoms and enhance daily living. Treatment plans are tailored to the progression of the condition but may include:

Nonsteroidal anti-inflammatory drugs (NSAIDs): This category of drugs help alleviate pain and inflammation.
Corticosteroids: In advanced instances, corticosteroids may be prescribed to control immune responses.
Antimalarial drugs: Medications like hydroxychloroquine can help controlling lupus flare-ups.

Regular monitoring and changing treatments as needed are important to keeping lupus under control.

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